RNAstructure is available as a graphical user interface for Windows a JAVA graphical user interface for Mac OS-X or Linux command line interfaces for Max OS-X, Linux, or Windows and source code for local compilation. These include chemical mapping, enzymatic mapping, NMR, and SHAPE data. Finally, RNAstructure can take a number of different types of experiment mapping data to constrain or restrain structure prediction. It can also predict secondary structures common to two, unaligned sequences, which is much more accurate than single sequence secondary structure prediction. It also can be used to predict bimolecular structures and can predict the equilibrium binding affinity of an oligonucleotide to a structured RNA target. It includes algorithms for secondary structure prediction, including facility to predict base pairing probabilities. RNAstructure is a complete package for RNA and DNA secondary structure prediction and analysis. RNAstructure, Version 6.4: Updated Decem( change log)
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